A new study led by Linlin Zhao, Professor of Chemistry and Director of the ETOX program, that also involved Professors Yinsheng Wang and Chia-En Chang, two other ETOX faculty members and other students and collaborators, identified a previously unknown type of DNA damage within the mitochondria. It is believed that the newly identified glutathionylated DNA adducts may provide insights into how our bodies sense and respond to stress. The study was recently published in the Proceedings of the National Academy of Sciences and was spotlighted in a UCR News article. This work builds upon earlier work conducted by an earlier ETOX graduate student Jiakei Yin and his advisor Yinsheng Wang in which they had identified GSH-DNA adducts in nuclear DNA. Our congratulations to Linlin, Yinsheng, Chia-En and their collaborators for this important research advance. [The figures above are from their PNAS article.]

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