Friday, April 19, 2024

Volatile Chemicals Alter Gene Expression in Fly and Mouse

In lab experiments, Sachiko Haga-Yamanaka, professor of Molecular, Cell and Systems Biology and ETOX faculty member in conjunction with other UCR colleagues including team leader Prof. Anandasankar Ray, exposed fruit flies to diacetyl, a microbial volatile compound released by yeast and common environmental agent, and found changes in gene expression in the fly’s antennae within several days. The team also found similar gene expression changes in the brains of mice and in human cells. The results suggest that the use of volatile chemicals could potentially be developed as a therapeutic approach to treat various diseases. Their results were recently published in the journal eLife and highlighted in UC Riverside News.  Our congratulations to Sachiko, Anand and colleagues for this nice recognition. [The figure above is from their eLife article.]

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