Professors Zhou and Chen Uncover Multigenerational Effects of Dicyclohexyl Phthalate

Changcheng Zhou and Qi Chen, professors in the Biomedical Sciences Division and Environmental Toxicology faculty members, and their colleagues have recently investigated the effects of paternal exposure to dicyclohexyl phthalate, or DCHP, on the metabolism of first generation (F1) and second generation (F2) offspring in mice.  As described in a UCR News article, "the researchers found that paternal DCHP exposure for four weeks led to high insulin resistance and impaired insulin signaling in F1 offspring. The same effect, but weaker, was seen in F2 offspring." Their research indicates that "paternal exposure to endocrine disrupting phthalates may have intergenerational and transgenerational adverse effects on the metabolic health of their offspring".  The research article has recently been published in Environment International. Our congratulations to Chengchang and Qi for this recognition of their important research.

 [The figure above is from the authors' Environment International article.]  

Toxicology and Risk Assessment Position with EPA in Midwest

The EPA Region 7 has an opening for a person with a toxicology and risk assessment background in its Lenexa, Kansas office.  The position is described as follows: Review literature, implements, and develops new methods in human health risk assessment and toxicology; Prepare reports and recommendations; and, Scientific collaboration.  More information can be found here.  Our thanks to ETOX alumnus Efrem Neuwirth for forwarding information about the position.  

Toxicologist Position at Massachusetts Department of Environmental Protection

The Massachusetts Department of Environmental Protection has an opening for a toxicologist in its Office of Research Standards (ORS), with a focus on Per- and Polyfluoroalkyl Substances (PFAS) and other persistent contaminants.  In this position, the successful applicant will be responsible for completing complex technical assessments of chemical toxicities and risks for priority PFAS and other emerging contaminants; assisting in the development of policy and method recommendations for standards and guidelines for such chemicals to protect public health; and conducting research in these and related areas. More information can be found here. Review of applications will begin on Feb. 23, 2023.