Monday, January 5, 2026

Professor Zhou and Colleagues Identify Important RNA Molecule Involved in Cardiovascular Health












A research team led by  Chengchang Zhou, Professor of Biomedical Sciences and an ETOX faculty member has identified a small transfer RNA-derived RNA that plays a major role in controlling cholesterol production within the body and likely plays a role in the development of heart disease.  Their work was recently published in the journal Nature Communications as was the focus of a recent UCR News article.  As described in in a , "the molecule, named tsRNA-Glu-CTC, could be a potential new target for future therapies aimed at lowering high cholesterol." Our congratulations to Chengchang and his colleagues for this important discovery which may open new therapeutic avenues understanding and treating cardio metabolic diseases.  [The figure above is from their Nature Communications article.]

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